Figure 2.

Behavioral scores (mean ± 1 SD) over 5 d after CLP for (A) female and (B) male mice divided by treatment. Five behavioral criteria (coat condition, breathing, activity, posture, and relation to other mice) were scored for 5 d after CLP and treatment with either saline or buprenorphine. Higher scores indicate more abnormal behaviors. No significant differences were seen in behavioral scores between saline- and buprenorphine-treated mice in either female or male BALB/c mice. Number varied by day due to mortality in both groups (day 1: female, n = 40 per group; male n = 10 per group; day 2: female, n = 17 to 21 per group; male, n = 6 per group; day 3: female, n = 17 to 21 per group; male, n = 5 or 6 per group; day 4: female, n = 15 to 18 per group; male n = 5 or 6 per group; day 5: female, n = 15 to 17 per group; male, n = 5 or 6 per group).