Table 1.
In vitro models of interest.
| References | Model | Scaffold | Construct type | Relevant details |
|---|---|---|---|---|
| Salimath and García, 2014 | C2C12 | PEG-MAL hydrogel | In vitro model | 3D model; variable stiffness; chemical functionalization |
| Egusa et al., 2013 | Mouse BMMSC; C2C12 | Fibrin on silicone | In vitro model | Differentiation due to mechanical stimulation, myogenic medium |
| Morimoto et al., 2013 | C2C12, primary mNSC | Matrigel | In vitro model | Self tension, NMJ formation |
| Nunes et al., 2013 | hPSC differentiated in cardiomyocites | Autologous ECM; collagen | In vitro model | Self assembly; electrical stimuli; wire structure |
| Palamà et al., 2013 | C2C12 | – | In vitro model | μtopography; LbL polyelectrolyte on glass |
| Shah et al., 2013 | Human masseter muscle cells | Biodegradable bacteriostatic phosphate glass fibers; collagen | In vitro model | μpatterning; self contraction |
| Snyman et al., 2013 | C2C12; pHMB | Neutralized collagen I hydrogel | In‘vitro model | Self contraction; reproducibility |
| Wang et al., 2013 | GFP-C3H myoblasts | Fibrin gel | In vitro model | Laminin, agrin formation; formation of NM receptors |
| Bian et al., 2012 | Neonatal sprague-dawley rat SM myoblasts | Matrigel-fibrin mesoscopically structured hydrogel | In vitro model | Self contraction; analysis of SM networks; electrical stimuli |
| Hosseini et al., 2012 | C2C12 | μstructured gelatin methacrylate | In vitro model | μpatterning; size analysis; electrical stimuli |
| Monge et al., 2012 | C2C12 | Patterned film (polyelectrolyte) | In vitro model | μpatterning; stiffness modification |
| Sharples et al., 2012 | Aged C2C12 (54x) | Collagen | In vitro model | Self contraction; reduced contractile force |
| Weist et al., 2012 | Primary cells from F344 soleus | Self produced ECM | In vitro model | TGF-β 1 effect evaluation; electrical stimuli; self contraction into 3D |
| Elmer et al., 2011 | C2C12; C3H10T1/2 | Electrospun PS | In vitro model | Chemical functionalization; μtopography |
| Li et al., 2011 | Primary myoblasts from C57/B6 mice; embryonic fibroblasts from E13/CF1 mice | Self produced ECM; fibrin | In vitro model | Self contraction and generation of 3D structures; cocolture |
| Pennisi et al., 2011 | C2C12 | Collagen I | In vitro model | Mechanical conditioning, uniaxial vs. multiaxial |
| van der Schaft et al., 2011 | H5V EC; C2C12 | Collagen I; self produced ECM | In vitro model | Self contraction; cocolture; effect of paracrine VEGF on vascularization and alignment |
| Lam et al., 2009 | Spreague-dawley rat soleus SC | Self-produced ECM | In vitro model | μpatterning; self assembly into 3D (roll-up) |
| Riboldi et al., 2008 | C2C12 | Degrapol | In vitro model | μpatterning |
| Engler et al., 2004 | C2C12; primary human fibroblasts | Patterned polyacrylamide gel | In vitro model | Mechanoregulation; cellular substrate |
| Dennis et al., 2001 | Primary sprague-dawley rat SC and FBs | Self produced ECM | In vitro model | Self contraction; self structuring 3D (roll up) |
BMMSC: Bone Marrow Mesenchimal Stem Cell. EC, Endothelial Cell; FB, FibroBlast; GFP, Green Fluorescent Protein; hPSC, human Pluripotent Stem Cell; mNSC, mouse Neural Stem Cell; NM, NeuroMuscular; NMJ, NeuroMuscular Junction; PEG-MAL, PolyEthylene Glycol-MALeimide; pHMB, primary Human MyoBlast; SC, Satellite cells; SM, Skeletal Muscle.