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. 2014 Sep 19;9:10.3402/ljm.v9.25431. doi: 10.3402/ljm.v9.25431

Table 3.

Effect of lemon grass volatile oil on carrageenan-induced paw edema in mice

LHP thickness (mm) (mean±SD) (% inhibition)

Treatment Dose (mg/kg) 30 min 90 min 240 min
Control 3.41±0.29a 2.916±0.03a 3.25±0.18a
Diclofenac (mg/kg, orally) 50 3.1±0.19b (86.20) 2.916±0.03a (69.23) 2.96±0.04b (88.88)
10 2.88±0.09b,c (66.66) 2.66±0.10b (82.75) 2.75±0.13b,c (96.82)
LGEO (mg/kg, by oral route) 40 2.76±0.13b,c (95.56) 2.68±0.16b (87.17) 2.7±0.14b,c (95.20)
100 2.88±0.07b,c (69.23) 2.68±0.14b (86.20) 2.75±0.10b,c (92.56)
200 2.88±0.098c (89.65) 2.68±0.11b {69.23) 2.73±0.12c (90.12)

Data are presented as mean (mm)±standard deviation (SD) (n=6/group). Groups of mice were pre-treated with vehicle (control group, oral administration, n=6), diclofenac (50 mg/kg, oral administration) or lemon grass essential oil (LGEO) at doses of 10, 40, 100, and 200 mg/kg (oral administration, n=6/group) 30 min before carrageenan-induced paw edema. LHP: left hind paw; LGEO: lemon grass essential oil. Means within the same column followed by the different letter are significantly different (P<0.05) according to ANOVA one-way analysis followed by Tukey's post hoc multiple comparison test.