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. 2014 Aug 8;6(3):133–141. doi: 10.1038/ijos.2014.44

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Copyright © 2014 West China School of Stomatology

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/

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Tooth phenotype in an M1V mutant ARHR patient. (a) Comparison of the amino acid sequence of the NH₂-terminal region of DMP1 across species, including the M1V mutant human DMP1. (b) Dental radiographs from an adult (20⁺ years old) ARHR patient (upper panel) and the age-matched control (lower panel). The patient had enlarged pulp cavities and root canals and reduced dentin thickness (arrows) compared to the control. ARGR, autosomal recessive hypophosphatemic ricket; DMP1, dentin matrix protein 1; Mut, mutation; yr., year.