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. 2014 Jul-Aug;25(4):168–175. doi: 10.5830/CVJA-2014-036

Table 5. Effects of infliximab therapy on conventional echocardiographic parameters versus prednisolone-treated patients.

Infliximab-treated RA patients (n = 20) Prednisolone-treated RA patients (n = 18)
Baseline 3-month p-value Baseline 3-month p-value p-value#
LV EDV (ml) 81.7 ± 6.6 79.7 ± 6.9 0.411 83.9 ± 4.7 85.4 ± 9.8 0.868 0.2
LV ESV (ml) 28.3 ± 4.2 27.2 ± 3.6 0.14 29.2 ± 5.3 27.9 ± 2.6 0.557 0.5
LV EF (ml) 63.8 ± 4.0 64.6 ± 2.8 0.096 64.1 ± 3.3 64.9 ± 2.8 0.35 0.71
IVS (mm) 9.7 ± 1.7 9.5 ± 3.9 0.267 9.5 ± 2.5 9.4 ± 4.6 0.316 0.06
PW (mm) 8.6 ± 0.6 8.3 ± 0.4 0.056 8.5 ± 0.8 8.7 ± 0.4 0.381 0.82
S′ (cm/sec) 7.2 ± 1.8 6.8 ± 0.8 0.258 7.4 ± 2.5 7.6 ± 0.6 0.369 0.1
E′ (cm/sec) 7.9 ± 2.5 9.0 ± 1.3 0.181 8.3 ± 1.9 7.8 ± 2.4 0.6 0.09
E/E′ 9.4 ± 3.9 8.0 ± 1.4 < 0.01 8.5 ± 2.5 8.8 ± 2.4 0.379 < 0.05
E (cm/s) 76.1 ± 7.4 76.0 ± 11.8 0.979 77.9 ± 8.2 79.5 ± 11.7 0.493 0.476
A (cm/s) 67.5 ± 9.9 66.0 ± 7.7 0.221 71.3 ± 11.2 70.2 ± 9.8 0.407 0.284
E/A 1.1 ± 0.2 1.1 ± 0.2 0.758 1.1 ± 0.2 1.1 ± 0.3 0.184 0.656
DT (ms) 199.1 ± 35.3 203.0 ± 34.1 0.609 198.6 ± 30.3 211.5 ± 22.4 0.055 0.858
IVRT (ms) 96.7 ± 10.8 95.3 ± 16.9 0.626 90.3 ± 10.1 90.3 ± 16.8 0.99 0.056

Values are expressed as mean ± SD.

#For comparisons between infliximab- and prednisolone-treated patients at baseline.

LV = left ventricle, EDV = end-diastolic volume, ESV = end-systolic volume, EF = ejection fraction, IVS = interventricular septum, PW = posterior wall, DT = deceleration time, IVRT = isovolumic relaxation time.