Table 6. Effects of infliximab therapy on left atrial echocardiographic and electrocardiographic parameters versus prednisolone-treated patients.
| Infliximab-treated RA patients (n = 20) | Prednisolone-treated RA patients (n = 18) | p-value# | |||||
| Baseline | 3-month | p-value | Baseline | 3-month | p-value | ||
| LAVImax (ml/m2) | 23.1 ± 2.9 | 21.9 ± 2.3 | < 0.05 | 23.7 ± 3.7 | 23.3 ± 2.1 | 0.453 | 0.435 |
| LAVIpreA (ml/m2) | 16.8 ± 2.7 | 15.8 ± 2.1 | < 0.01 | 17.5 ± 3.0 | 17.6 ± 3.1 | 0.892 | 0.369 |
| LAVImin (ml/m2) | 11.4 ± 2.2 | 11.0 ± 2.1 | 0.082 | 10.4 ± 2.9 | 10.1 ± 1.5 | 0.368 | 0.066 |
| Pmax (ms) | 86.0 ± 8.8 | 82.0 ± 10.5 | 0.072 | 91.6 ± 8.5 | 87.7 ± 10.6 | 0.09 | 0.052 |
| Pmin (ms) | 42.5 ± 7.8 | 41.0 ± 12.5 | 0.505 | 43.8 ± 6.9 | 42.7 ± 14.4 | 0.749 | 0.568 |
| P dispersion (ms) | 43.5 ± 7.4 | 41.0 ± 7.1 | 0.056 | 47.7± 4.2 | 45.0 ± 7.8 | 0.172 | < 0.05 |
| LA global strain (%) | 25.4 ± 10.6 | 30.4 ± 2.6 | < 0.05 | 31.5 ± 14.7 | 36.3 ± 6.9 | 0.21 | 0.181 |
| LA global systolic strain rate (ms) | 1.6 ± 0.3 | 1.7 ± 0.2 | 0.073 | 1.7 ± 0.3 | 1.7 ± 0.4 | 0.536 | 0.59 |
| LA global early diastolic strain rate (/s) | –1.1 ± 0.3 | –1.2 ± 0.3 | 0.098 | –1.2 ± 0.3 | –1.2 ± 0.2 | 0.751 | 0.596 |
| LA global late diastolic strain rate (/s) | –1.2 ± 0.2 | –1.2 ± 0.2 | 0.567 | –1.0 ± 0.2 | –1.1 ± 0.2 | 0.367 | < 0.01 |
Values are expressed as mean ± SD.
#For comparisons between infliximab- and prednisolone-treated patients at baseline.
LA = left atrium, LAVI = left atrial volume index.