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. Author manuscript; available in PMC: 2014 Sep 22.
Published in final edited form as: Autophagy. 2009 Nov 13;5(8):1099–1106. doi: 10.4161/auto.5.8.9825

Figure 6.

Figure 6

Supression by 3-methyladenine, cyclosporin A and NIM811 of autophagosomal proliferation. LTR uptake by cultured hepatocytes was assessed using a fluorescence plate reader, as described in Material and Methods. As indicated, hepatocytes were pretreated 30 min with 10 mM 3MA, 5 µM CsA, 5 µM NIM811 or 5 µM tacrolimus (FK506) before addition of LTR. Values are means ± SEM (n = 16 per group). On Days 2 and 3, all treated groups except tacrolimus were significantly different (p < 0.01) than the untreated group (None).