| Amisulpride (Solian) |
50 mg/day |
50-300 mg for negative symptoms, 400-800 mg for positive symptoms |
Once daily. If more than 400 mg, twice daily |
Insomnia, anxiety, agitation, somnolence, nausea, dry mouth, acute dystonia, galactorrhoea |
| Aripiprazole (Abilify) Generic available
|
10-15 mg/day |
10-30 mg/day |
Once daily |
Agitation, constipation, EPS, insomnia, nausea, somnolence |
| Olanzapine (Zyprexa) |
5-10 mg/day |
10-20 mg/day |
Once daily |
Constipation, dizziness, dry mouth, impaired glucose tolerance (IGT), hyperlipidaemia, increased appetite, sedation, weight gain |
| Quetiapine (Seroquel) |
50 mg/day |
300-800 mg/day |
Twice daily |
Dry mouth, IGT, headache, hyperlipidaemia, increased appetite and weight, orthostatic hypotension, sedation |
| Paliperidone (Invega) |
3 mg/day |
6-12 mg/day |
Once in the morning |
EPS, IGT, galactorrhoea, hyperlipidaemia, menstrual irregularity, orthostatichypotension, prolactin elevation, sedation, sexual dysfunction, tardive dyskinesia, weight gain |
| Risperidone (Risperdal) Generic available
|
1-2 mg/day |
2-6 mg/day |
Once daily |
| Risperidone microspheres long-acting injection (Consta) |
25 mg/2 weeks |
25-50 mg every 2 weeks |
Once every 2 weeks |
| Clozapine (Clozaril) Generic available
|
12.5 mg/day |
300-900 mg/day (serum level for doses >600 mg/day) |
Twice daily |
Agranulocytosis, excess salivation, fever, IGT, hyperlipidaemia, increased appetite, myocarditis, orthostatic hypotension, sedation, seizures, tachycardia, weight gain |
| Chlorpromazine (CPZ) |
50-100 mg/day |
300-1000 mg/day |
3 times daily |
Constipation, dry mouth, EPS, orthostatic hypotension, photosensitivity, sedation, tachycardia, tardive dyskinesia |
| Perphenazine |
4-8 mg/day |
16-64 mg/day |
3 times daily |
| Fluphenazine depot (Modecate) Generic available
|
12.5-25 mg IM/ 1-3 weeks |
6.25-50 mg IM every 2-4 weeks |
Every 1-3 weeks |
| Flupenthixol decanoate (Fluanxol) |
10-20 mg IM/ 1-3 weeks |
10-40 mg IM every 2-4 weeks |
Every 1-3 weeks |
| Haloperidol |
2-5 mg/day |
2-20 mg/day |
1-3 times daily |
| Sulpiride Generic available
|
200-400 mg daily |
400-800 mg daily |
Twice daily |
| Zuclopenthixol acetate (Acuphase) |
50-100 mg IM/ 2-3 days |
50-200 mg/3 days |
- |
| Zuclopenthixol decanoate (Clopixol depot) |
100-200 mg IM/ 1-3 weeks |
100-400 mg/ 1-3 weeks |
Every 1-3 weeks |
