Tutor:	What are the problems in this boy?
Student:	Obesity, sedentary lifestyle, playing video games, watching TV, excessive eating, poor school performance, hyperactivity, and attention deficit
Tutor:	What among these do you think is the main problem?
Student:	Obesity (other students may have different choices)
Tutor:	Why?
Student:	Because obesity may lead to many problems later on in life, such as metabolic syndrome.
Tutor:	I see. Why do you say that?
Student:	From what we read, problems in obesity are well known.
Tutor:	So, are you suggesting that all obese children will develop metabolic syndrome?
Student:	…not all, but many will.
Tutor:	Aren’t there many non-obese children who develop metabolic syndrome later in life? What makes you particularly concerned about obese children like this boy that you have just seen?
Student:	…yes, everyone has some risk, but I think obese children have higher risk.
Tutor:	Higher risk compared to…
Student:	Non-obese children
Tutor:	I see. How much higher is the risk do you think?
Student:	…I am not sure.
Tutor:	So, what specifically are you not sure about?
Student:	How much higher is the risk of developing metabolic syndrome in obese children compared to non-obese children.
Tutor:	Excellent, there you have identified an important information gap. So, what should we do to fill that gap?
Student:	We should search for the answers.
Tutor:	Before we start searching, it is better if we plan to see what key words we should use for our search using the PICO framework. Let’s fit the terms into Patient (P), prognostic Indicator (I), Comparison (C), and Outcome (O).