Table 2.
Brain regional volumes (mean ± s.d.) in mm3 for high and low CD14+ HIV DNA subject groups.
| Brain region | Low HIV DNA (N=24) | High HIV DNA (N=36) | p |
|---|---|---|---|
| Corpus callosum | 3044.96 ± 416.63 | 2865.06 ± 341.10 | 0.135 |
| Brainstem | 19,211.00 ± 3096.09 | 17,523.081 ± 1917.51 | 0.033 |
| Thalamus | 13,253.58 ± 1392.82 | 12,604.81 ± 1184.10 | 0.115 |
| Caudate | 6620.46 ± 688.51 | 6438.56 ± 793.29 | 0.571 |
| Putamen | 10,411.71 ± 1152.89 | 10,076.28 ± 1113.60 | 0.520 |
| Globus pallidus | 3098.96 ± 437.09 | 2996.61 ± 337.16 | 0.534 |
| Hippocampus | 8707.83 ± 1082.94 | 8176.17 ± 955.30 | 0.127 |
| Amygdala | 3139.54 ± 539.36 | 2915.89 ± 385.02 | 0.146 |
| Nucleus accumbens | 1228.38 ± 286.04 | 1064.42 ± 195.21 | 0.021 |
| Cerebellar gray matter | 96,601.96 ± 14,794.45 | 90,543.42 ± 11,648.79 | 0.205 |
| Cerebellar white matter | 25,555.42 ± 3435.41 | 24,194.28 ± 3670.74 | 0.364 |
| Subcortical gray matter | 170,245.88 ± 21,979.89 | 159,741.67 ± 15,420.27 | 0.073 |
| Cortical gray matter | 430,814.53 ± 42,953.45 | 410,606.54 ± 37,892.17 | 0.101 |
| Cerebral WM | 448,941.97 ± 62,096.01 | 424,394.91 ± 44,337.71 | 0.232 |
| Total gray matter | 601,060.40 ± 59,894.84 | 570,348.20 ± 49,084.61 | 0.045 |
| Lateral ventricles | 10,145.75 ± 6351.26 | 9993.11 ± 5956.19 | 0.966 |
Effects of CD14+ HIV DNA on volumetric group differences were assessed by ANCOVA controlling for age, log CD4 and ICV.