Table 2. Univariate analysis between clinical variables and overall survival (Cox regression model).

		OS (months)	HR (95%CI)	p-value
Gender	Male	9.23 (5.27-13.20)	1.24 (0.68-2.25)	0.488
	Female	11.63 (8.63-14.63)
Tobacco history	Current	14.82 (9.55-20.08)	2.31 (1.36-3.93)	0.002
	Former	6.77 (1.78-11.76)
PS	0-1	14.82 (11.77-17.87)	3.64 (2.18-6.09)	<0.001
	2-4	3.81 (0.96-6.66)
Treatment	Yes	11.70 (8.48-14.91)	0.061 (0.024-0.15)	<0.001
	No	0.76 (0.84-1.43)
Stage	I-III	33.25 (19.26-47.24)	4.18 (2.05-8.50)	<0.001
	IV	8.80 (7.49-10.11)
Response to first line	Yes	12.32 (8.95-15.69)	1.77 (0.75-4.22)	0.194
	No	6.21 (1.31-11.10)
sHGF (pg/ml)	<1886	12.58 (6.03-19.14)	2.02 (1.21-3.37)	0.007
	>=1886	7.75 (5.11-10.39)