Table 1. Functional classification of genes with more than 3fold modilation in response to miRNA- mediated BSP knockdown; comparison of the B3 and B7 cell clones.

Functional classes	Gene Symbol	Gene Full Name	Fold change
		(B 3)	(B 7)
Transcriptional regulators	FOS	FBJ murine osteosarcoma viral oncogene homolog	11.32	1.99
	DDIT3	DNA-damage-inducible transcript 3	6.52	2.43
	ATF3	activating transcription factor 3	5.01	1.93
	EGR1	early growth response 1	4.12	1.20
	CREBRF	CREB3 regulatory factor	3.31	1.82
	ID2	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein	3.16	1.79
Cytokines	IL8	interleukin 8	4.93	4.14
	SCG2	secretogranin II	3.72	1.76
	IL11	interleukin 11	−3.74	−2.02
Immune response	IFIT2	interferon-induced protein with tetratricopeptide repeats 2	7.64	3.45
	KLRC2	killer cell lectin-like receptor subfamily C, member 2	4.00	2.21
Signal transduction	SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	3.61	3.81
	DDIT4	DNA-damage-inducible transcript 4	3.80	2.08
Calcium ion binding	S100P	S100 calcium binding protein P	2.58	4.27
	MEGF6	multiple EGF-like-domains 6	4.65	3.04
Angiogenesis	ANGPTL4	angiopoietin-like 4	4.39	1.92
ECM protease	MMP9	matrix metallopeptidase 9	1.01	3.30
Histones	HIST2H2AA3	histone cluster 2, H2aa3	11.26	2.66
	HIST1H2BD	histone cluster 1, H2bd	10.15	3.42
	HIST1H4A	histone cluster 1, H4a	7.59	1.10
	HIST1H1C	histone cluster 1, H1c	7.30	1.89
	HIST2H2AC	histone cluster 2, H2ac	7.13	1.99
	HIST1H2AC	histone cluster 1, H2ac	6.53	2.54
	H2AFJ	H2A histone family, member J	3.44	1.79
	HIST1H2BK	histone cluster 1, H2bk	3.05	1.01
Metabolism	CYP1B1	cytochrome P450, family 1, subfamily B, polypeptide 1	7.25	2.76
	CTH	cystathionase (cystathionine gamma-lyase)	3.10	1.73
RNA	RN7SK	RNA, 7SK small nuclear	5.93	1.91
	RNA28S5	RNA, 28S ribosomal 5	2.44	3.13
	SNORD3A	small nucleolar RNA, C/D box 3A	4.70	1.41