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. 2014 Jul 9;5(14):5764–5781. doi: 10.18632/oncotarget.2180

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Copyright: © 2014 Perry et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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A Western blots demonstrate expression of APE1 (A1), NBN (A2), PTEN (A3) and PMS2 (A4) in LN229 (1) and LN18 (2) glioma cell lines. B Human glioma sections stained using immunohistochemistry technique and the addition of no primary antibody (B1), APE1 (B2), NBN (B3), PTEN (B4) and PMS2 (B5). C Kaplan Meier survival curves for overall survival in high grade glioma patients in the Nottingham cohort stratified by APE1 (C1), NBN (C2), nuclear PTEN (C3), cytoplasmic PTEN (C4), PMS2 (C5) and APE1/PTEN combination (C6) protein expression. Also Kaplan Meier survival curves for overall survival in glioblastoma patients in the Test (C7) and TCGA (C8) datasets stratified by APE1/PTEN combination mRNA expression.