Figure 4. Soluble MICA protein levels were regulated by miRNA93 in human primary hepatocytes.
a, Membrane-bound MICA protein expression was not affected by miRNA delivery into human primary hepatocytes. Flow cytometric analysis of membrane-bound MICA protein expression in cells delivered BNC-mediated control (green line), let7g (blue line), or miRNA93 (red line). Gray-shaded histograms represent background staining, assessed using isotype IgG. Representative results from three independent experiments are shown. b, Soluble MICA protein levels in the supernatants of primary hepatocytes after delivery of the indicated miRNAs (let7g or miRNA93) or negative control (NC) with or without HBV replication. Data represent the means ± s.d. of three independent experiments. *p<0.05.