Figure 4. Representative immunohistochemical staining of Glo-1 expression in triple negative versus triple positive human breast tissues.

Glo-1 expression was evaluated in triple negative (n= 21) and triple positive (n= 21) breast cancer patients and one representative case of each is shown in panel A (c, d). The staining of Glo-1 was compared with the immunostaining for Arg-pyrimidine accumulation in the same triple negative (a) and triple positive (b) human specimen. Glo-1 is highly expressed in both triple positive and triple negative tumors and there was no significant difference between the two breast cancer subtypes. Glo-1 immunohistochemical quantification is shown in panel (B). The evaluation of the staining was performed as described in Materials and Methods section. Magnification 100x.