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. 2014 Jun 26;5(14):5602–5614. doi: 10.18632/oncotarget.2136

Fig.1. The mRNA level of NUMB-1 is decreased in ESCC tissues and correlates with poor prognosis in patients.

Fig.1

Semi-quantitive PCR was performed to detect NUMB-1 mRNA levels in ESCC tissues and adjacent normal tissues resected from 75 patients. (A) A representative image showing decreased NUMB-1 mRNA levels in 10 out of 15 pairs of tissue. (B) Kaplan–Meier analysis showed that patients in the low NUMB-1 group (n=50) experienced a significantly shorter EFS (median EFS: 16 months vs 45 months, p=0.023, log-rank test) and overall survival (OS) (median OS: 24 months vs 49 months, p=0.012, log-rank test) than patients in the high NUMB-1 group (n=25).