Table 1. Average B score summary of gene hits.

Summary of the 31 gene hits identified to significantly decrease tumor cell proliferation. Clone references for the specific lentiviral constructs used to generate growth effects are shown. Average B-scores (n=3) for all four cell lines tested are provided.

Gene	Description	Clone reference	ACHN	Caki1	Caki2	KIJ265T
ADM	Adrenomedullin	NM_001124.1-441s1c1	−2.903	−3.823	−2.025	−2.025
		NM_001124.1-643s1c1	−3.001	−2.591	−1.677	−3.357
ANGPTL4	Angiopoietin like 4	NM_139314.1-1618s1c1	−5.296	−2.924	−2.001	−2.033
BHLHB3 (BHLHE41)	basic helix-loop-helix family, member e41	NM_030762.1-452s1c1	−1.825	ns	−2.134	−2.135
BTK	Bruton agammaglobulinemia tyrosine kinase	NM_000061.x-1873s1c1	−2.113	−1.549	ns	−2.4395
		NM_000061.x-1066s1c1	ns	−3.331	−1.772	ns
CAMK1	calcium/calmodulin-dependent protein kinase I	NM_020397.x-399s1c1	−2.248	−1.752	−1.646	−1.645
CDH13	cadherin 13, H-cadherin	NM_001257.2-1389s1c1	−2.914	−3.173	−1.848	ns
CEP290	centrosomal protein 290	NM_025114.1-1983s1c1	−2.408	−1.431	−3.755	−2.5605
C20ORF100 (TOX2)	TOX high mobility group box family member 2	NM_032883.1-1312s1c1	−2.688	−3.526	−2.119	−3.542
EDNRA	Endothelin receptor type A	NM_001957.1-1501s1c1	−2.536	−2.567	ns	ns
		NM_001957.1-1543s1c1	ns	ns	−2.523	−2.417
EFCAB3	EF-hand calcium binding domain 3	NM_173503.1-313s1c1	−1.384	−1.678	−1.862	−3.624
		NM_173503.1-535s1c1	−1.577	−3.152	−2.362	−2.267
EGFR	Epithelial growth factor receptor	NM_005228.3-396s1c1	−1.649	−2.03	−2.25	−1.3725
ENPP3	ectonucleotide pyrophosphatase, phosphodiesterase 3	NM_005021.2-1177s1c1	−1.613	−3.066	−2.129	−2.664
		NM_005021.2-83s1c1	−2.074	−3.485	ns	−2.8245
FXYD5	FXYD domain containing ion transport regulator 5 (dysadherin)	NM_014164.3-543s1c1	−2.671	−1.979	−3.656	−1.541
IGFBP3	insulin-like growth factor binding protein 3	NM_000598.4-711s1c1	−3.87	−2.924	ns	−2.892
		NM_000598.4-633s1c1	−1.975	−4.058	−2.094	−1.626
KCNJ2	Potassium inwardly-rectifying channel, subfamily J, member 2	NM_000891.2-1321s1c1	−2.506	−2.78	−1.027	−1.387
		NM_000891.2-1116s1c1	−1.836	−1.95	−2.25	ns
KISS1R	kisspeptin (metastin) receptor 1 (GPR54)	NM_032551.2-342	−6.549	−5.103	−4.533	−7.964
KSR1	kinase suppressor of ras 1	XM_290793.4-1852s1c1	−4.653	−3.977	−2.734	−2.433
LAMA4	laminin, alpha 4	NM_002290.2-1258s1c1	ns	−3.011	−2.147	−5.5775
LOXL2	lysyl oxidase-like 2	NM_002318.1-769s1c1	−1.157	−2.416	−2.369	−4.7325
		NM_002318.1-2416s1c1	−4.78	−1.12	−2.164	ns
MYC	v-myc myelocytomatosis viral oncogene homolog	NM_002467.2-1377s1c1	−3.371	−3.246	−2.473	−2.416
NNMT	Nicotinamide N-methyltransferase	NM_006169.1-711s1c1	−3.947	−2.136	−2.396	−2.168
		NM_006169.1-801s1c1	−2.255	−1.909	−1.493	ns
NPTX2	Neuronal pentraxin II	NM_002523.1-1623s1c1	−1.825	−1.999	−2.271	−1.438
		NM_002523.1-1316s1c1	−1.619	−2.92	−3.08	−1.504
OLFML2A	olfactomedin-like 2A	NM_182487.1-975s1c1	−2.711	ns	−3.566	−2.907
PGBD5	piggyBac transposable element derived 5	NM_024554.2-142s1c1	−6.624	−2.965	−2.87	−7.0545
PLOD2	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2	NM_000935.1-532s1c1	−1.649	−1.642	−2.14	−1.94
RAPGEF5	Rap guanine nucleotide exchange factor (GEF) 5	NM_012294.2-105s1c1	−3.625	−2.346	−1.932	−2.182
SCD	Stearoyl-CoA desaturase	NM_005063.3-1200s1c1	−2.216	−1.495	−2.192	−3.231
		NM_005063.3-780s1c1
SEMA6A	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	NM_020796.1-1890s1c1	−2.348	−2.099	−1.606	−1.626
SSPN	sarcospan (Kras oncogene-associated gene)	NM_005086.3-352s1c1	−3.359	−2.424	−2.326	−2.325
TCF8 (ZEB1)	zinc finger E-box binding homeobox 1	NM_030751.2-70s1c1	−1.72	−2.388	−2.205	ns
TMCC1	transmembrane and coiled-coil domain family 1	NM_015008.1-1345s1c1	−2.527	−2.583	−2.864	−2.1195