Skip to main content
. 2014 Jun 17;5(14):5350–5368. doi: 10.18632/oncotarget.2110

Fig.7. Oncostatin M and Eotaxin Overespression in Hypoxic Regions of Human Breast Cancer Specimen, with Concurrently Upregulated CD206-expressing M2-Macrophages.

Fig.7

(A) H&E staining revealing distinct tumor architecture in human breast cancer specimens (patient #3) (B) Representative examples of presence of Oncostatin M in hypoxic regions of breast cancer specimen (patient 3) as detected through immunohistochemical staining for hypoxia specific biomarker HIF1α and Oncostatin M. (C) Representative examples of presence of Eotaxin in hypoxic regions of breast cancer specimen as detected through immunohistochemical staining for hypoxia specific biomarker HIF1α and Eotaxin. (D-E) Oncostatin M and Eotaxin positive regions of breast cancer specimen coincided with CD206 enriched regions.