Table 3. Univariate and multivariate Cox-regression analysis for overall survival in NPC patients (n = 95).
| Variable | Univariate analysis (OS) | Multivariate analysis (OS) | ||||
|---|---|---|---|---|---|---|
| Hazard Ratio | 95% confidence interval | p | Hazard Ratio | 95% confidence interval | P | |
| Age ≥44 (VS. <44) | 1.119 | 0.454 to 2.756 | 0.807 | 1.177 | 0.438 to 3.160 | 0.747 |
| Gender Male vs. Female | 0.930 | 0.334 to 2.587 | 0.889 | 1.265 | 0.425 to 3.763 | 0.672 |
| Histopathologic characteristics Undifferentiated carcinoma (VS. others) | 0.048 | 0 to 1.636E4 | 0.640 | 0.000 | 0.000 | 0.987 |
| Lymph node status Positive (VS. Negative) | 4.800 | 0.640 to 36.034 | 0.127 | 2.531 | 0.319 to 20.061 | 0.379 |
| Initial clinical stage III+IV (VS. I+II) | 2.284 | 0.665 to 7.847 | 0.190 | 2.226 | 0.338 to 14.667 | 0.406 |
| Tumor stage T3+T4 (VS. T1+T2) | 1.785 | 0.642 to 4.963 | 0.266 | 1.249 | 0.253 to 6.179 | 0.785 |
| Recurrence Yes (VS. No) | 2.553 | 0.842 to 7.741 | 0.098 | 1.143 | 0.353 to 3.700 | 0.824 |
| Metastatic Yes (VS. No) | 3.538 | 1.386 to 9.031 | 0.008 | 3.021 | 1.038 to 8.794 | 0.043 |
| Skp2 High (Vs. No) | 10.122 | 2.931 to 34.952 | <0.001 | 8.215 | 2.236 to 30.172 | 0.002 |