. Author manuscript; available in PMC: 2014 Sep 22.

Published in final edited form as: Invest New Drugs. 2010 Apr 7;29(5):818–826. doi: 10.1007/s10637-010-9429-z

Table 1.

Induction of apoptosis (A) and mitochondrial potential damage (B) by atiprimod at equipotent concentrations (IC₅₀ and IC₈₀) in FDCP-EpoR cell lines transduced with either JAK2^WT or JAK2^V617F

		FDCP-EpoR JAK2^WT			FDCP-EpoR JAK2^V617F
		0	IC₅₀	IC₈₀	0	IC₅₀	IC₈₀
A. Apoptosis (% Annexin V positive)	48 h	11 (±2)	17 (±3)	96 (±7)	14 (±2)	46 (±1)	89 (±5)
A. Apoptosis (% Annexin V positive)	72 h	18 (± 2)	33 (±5)	97 (±10)	17 (±7)	57 (±3)	95 (±9)
B. Mitochondrial membrane potential (% CMX negative)	48 h	16 (±2)	32 (±4)	99 (±6)	8 (±4)	18 (±6)	89 (±4)
B. Mitochondrial membrane potential (% CMX negative)	72 h	15 (±4)	44 (±4)	99 (±4)	14 (±6)	23 (±8)	99 (±7)