Table 2. Associations of complement factor H (CFH) Y402H, ARMS2 A69S, and complement component 3 (C3) R102G with AMD in the study population.
SNP | Variant | Genotype | OR | 95% CI | P-value | |
---|---|---|---|---|---|---|
CFH Y402H | YH | TC | 1.99 | 1.77 | 2.22 | |
HH | CC | 3.94 | 3.14 | 4.95 | 4.40 × 10-30 | |
ARMS2 A69S | AS | GT | 2.04 | 1.82 | 2.29 | |
SS | TT | 4.08 | 3.30 | 5.26 | 2.10 × 10-29 | |
C3 R102G | RG | CG | 1.39 | 1.21 | 1.57 | |
GG | GG | 1.93 | 1.46 | 2.46 | 4.30 × 10-06 |