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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: JAMA Ophthalmol. 2014 Jan;132(1):84–95. doi: 10.1001/jamaophthalmol.2013.5506

Table 5. Results of logistic regression models for log-additive versus recessive associations between 15 CX3CR1 SNPs with age-related macular degeneration using pooled data from 5 study populations.

Additive Models Recessive Models

Adjusted for age, sex, smoking, and obesity Also adjusted for CFH, ARMS2, C3 Adjusted for age, sex, smoking, and obesity Also adjusted for CFH, ARMS2, C3

SNP OR P-value OR P-value Permutation P-value OR P-value OR P-value Permutation P-value
rs3732378 0.92 0.24 0.87 0.074 0.062 0.92 0.7 0.92 0.72 0.75
rs3732379 1.02 0.80 1.01 0.85 0.86 1.09 0.54 1.09 0.58 0.59
rs2669845 1.15 0.069 1.14 0.12 0.14 1.38 0.28 1.28 0.43 0.61
rs2853712 1.00 0.97 1.00 0.96 0.99 1.01 0.91 0.99 0.93 0.91
rs11715522 1.08 0.18 1.11 0.073 0.084 1.26 0.027 1.27 0.034 0.038
rs2853711 0.99 0.89 0.96 0.52 0.42 1.14 0.33 1.12 0.43 0.52
rs1014638 1.02 0.67 1.02 0.77 0.79 1.15 0.30 1.09 0.58 0.54
rs13062158 1.01 0.80 1.05 0.46 0.52 1.23 0.13 1.18 0.27 0.25
rs2853707 0.91 0.15 0.88 0.069 0.066 0.89 0.50 0.83 0.31 0.27
rs9862876 1.00 0.94 0.99 0.82 0.84 1.04 0.80 1.08 0.64 0.55
rs12636547 0.87 0.12 0.85 0.098 0.10 0.62 0.28 0.60 0.32 0.20
rs17793056 0.94 0.25 0.93 0.21 0.19 0.98 0.83 0.93 0.43 0.41
rs17038640 1.04 0.45 1.07 0.25 0.21 1.13 0.29 1.14 0.31 0.28
rs9868689 0.97 0.62 0.97 0.68 0.71 0.95 0.77 1.00 0.98 0.95
rs1877563 0.85 0.056 0.84 0.056 0.060 0.80 0.56 0.89 0.76 0.79