Figure 2.
Regulation of Cav-1 promoter activities. pLuc-Cav, pRL, pStat3DN, or pcDNA3.1 were transfected into 231-BR (A) or BT474-BR cells (B) for 48 h; 231-BR (C & E) and BT474-BR cells (D & F) were transfected with pLuc-Cav and pRL for 24 h, and the cells were then treated with DMSO (10 µM), 10 µM STA-21, or 10 µM JSI-124 for 24 h. The caveolin-1 promoter activity was measured and expressed as the fold change relative to that in the control group. Each column indicates the mean± standard error from results of three different experiments. *P < 0.05; **P < 0.01.