Table 1. Information of 10 Crystal Structures of GPCRs Used in the Present Worka.
SMO | bovine rhodopsin | CXCR4 | M2MAR | D3R | β2AR | A2AAR | H1R | S1P | β1AR | |
---|---|---|---|---|---|---|---|---|---|---|
PDB entry | 4JKV | 1F88 | 3ODU | 3UON | 3PBL | 2RH1 | 2YDO | 3RZE | 3V2W | 2Y00 |
resolution (Å) | 2.45 | 2.40 | 2.50 | 3.00 | 2.89 | 2.40 | 3.00 | 3.10 | 3.35 | 2.50 |
whole sequence identity (±2%) | 14.4 | 17.4 | 19.1 | 20.9 | 23.5 | 24.4 | 25.1 | 25.2 | 28.5 | 28.5 |
sequence identity in TM (±2%) | 18 | 25 | 21 | 27 | 28 | 28 | 29 | 30 | 34 | 35 |
proSA-web Z-score | –2.80 | –2.82 | –3.54 | –3.24 | –2.72 | –4.21 | –4.87 | –3.36 | –3.49 | –4.33 |
ref | (35) | (19) | (37) | (31) | (38) | (30) | (33) | (34) | (32) | (36) |
We listed the information on 10 GPCRs used in the present work, including PDB entry, resolution, sequence identity to CB2, and the related references.