. 2014 Aug 20;54(9):2483–2499. doi: 10.1021/ci5002718

Table 2. Binding Affinities (K_i, nM) of Ligands to Cannabinoid Receptors of Wild-Type and Mutant CB2 Stably Expressed in CHO Cells^a.

receptors	WT	V113E	V113L	F183Q	F183V	F281K
SR144528	3.2 (1.1–8.8)	ND	6.1 (2.8–12)	ND	ND	ND
CP55940	2.7 (1.5–4.8)	ND	3.8 (0.3–46)	ND	ND	ND

Data are the means and corresponding 95% confidence intervals of two independent experiments each performed in duplicate. WT: wild-type; V113E, V113L, F183Q, F183V, and F281K: mutant huCB2.ND: binding not detected.

Table 2. Binding Affinities (Ki, nM) of Ligands to Cannabinoid Receptors of Wild-Type and Mutant CB2 Stably Expressed in CHO Cellsa.

Table 2. Binding Affinities (K_i, nM) of Ligands to Cannabinoid Receptors of Wild-Type and Mutant CB2 Stably Expressed in CHO Cells^a.