Table 4. Frequency of Application of Ring–Chain Rules in the Systematic Generation of Ring–Chain Tautomers in AMS Database.

SMIRKS rule	count	%
3-exo-trig	65 435	0.31
4-exo-trig	10 560	0.05
5-exo-trig	7 506 722	35.09
6-exo-trig	5 289 114	24.72
7-exo-trig	4 185 292	19.56
5-exo-dig	179 567	0.84
6-exo-dig	472 074	2.21
7-exo-dig	3 293 445	15.40
5-endo-trig	169 007	0.79
6-endo-trig	156 371	0.73
7-endo-trig	65 239	0.30