Table 1.
Characteristics of sample
| Characteristics | N | Mean (SD)/n (%) | Range |
|---|---|---|---|
| Age, years | 91 | 53.4 (7.9) | 36–69 |
| Female | 91 | 63 (69.2%) | |
| Education, years | 91 | 16.3 (2.9) | 8–23 |
| Any E4 allele | 91 | 33 (36.3%) | |
| Body mass index, kg/m2 | 91 | 27.8 (5.5) | 19.2–47.8 |
| Vitamin C supplements | 91 | 22 (24.2%) | |
| Vitamin E supplements | 91 | 20 (22.0%) | |
| Blood pressure medications | 91 | 11 (12.1%) | |
| Systolic blood pressure, mm Hg | 91 | 121.6 (13.4) | 94–161 |
| Total cholesterol, mg/dL | 91 | 190.7 (32.4) | 114–299 |
| HDL cholesterol, mg/dL | 91 | 56.0 (16.5) | 31–122 |
| LDL cholesterol, mg/dL | 91 | 118.8 (29.6) | 41–215 |
| Trigylcerides, mg/dL | 91 | 99.7 (43.8) | 46–246 |
| Glucose, mg/dL | 90 | 83.4 (7.2) | 72–109 |
| MMSE, points of 30 | 90 | 29.5 (0.7) | 27–30 |
| HVLT-total learning score | 91 | 29.6 (3.4) | 20–35 |
| HVLT-delayed recall score | 91 | 10.5 (1.8) | 3–12 |
| Processing speed index | 91 | 90.8 (12.6) | 57–119 |
| Mental control total score | 91 | 30.3 (4.9) | 19–40 |
| Working memory composite score | 91 | 26.4 (4.2) | 14–37 |
| Stroop color-word score | 91 | 43.1 (7.7) | 26–69 |
| CSF ABx-38 by MSD, ng/L | 91 | 1575.7 (661.7) | 405–4042 |
| CSF ABx-40 by MSD, ng/L | 91 | 6662.9 (2015.8) | 2710–13,235 |
| CSF ABx-42 by MSD, ng/L | 91 | 524.6 (202.9) | 155–1315 |
| CSF AB1-42 by xMAP, ng/L | 91 | 344.1 (69.0) | 150–510 |
| CSF tau by xMAP, ng/L | 91 | 63.4 (25.0) | 27–132 |
| CSF p-tau by xMAP, ng/L | 91 | 36.4 (18.6) | 13–127 |
| CSF nucleated cells, cells/uL | 91 | 2.05 (2.42) |
Key: MMSE, Mini-Mental State Examination. HVLT, Hopkins Verbal Learning Test. CSF, Cerebrospinal Fluid. AB, amyloid-beta. MSD, Meso Scale Discovery electrochemiluminescence. xMAP. INNO-BIA AlzBio3.