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. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: Neuropharmacology. 2014 May 4;85:190–197. doi: 10.1016/j.neuropharm.2014.04.015

Fig. 2. Effects of intra-BLA infusion of AP5 or ATPA on stress-induced anxiety-like behavior.

Fig. 2

(A) Stressed mice showed significantly reduced body weight as compared to non-stressed controls (con). (B) Stressed mice spent a greater percentage of time in the light compartment than non-stressed controls following intra-BLA infusion of vehicle, but not after intra-BLA AP5 or ATPA infusion. Mice infused with AP5 showed spent more time in the light compartment than vehicle-infused mice, irrespective of stress. (C) Mice infused with AP5 made more entries into the light compartment than vehicle-infused controls, irrespective of stress. (D) Stressed mice traveled farther overall (inset) as well as in the light compartment than non-stressed controls following infusion of vehicle, but not after intra-BLA ATPA infusion. Mice infused with AP5 traveled farther overall and in the light dark compartment than vehicle-infused controls, an effect which was augmented by stress. Data are means ± SEM. *P < .05 stress versus non-stressed controls receiving the same treatment, #P < .05 AP5 versus vehicle or ATPA. n = 6–9 per group.

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