Fig. 3. Effects of stress on BLA synaptic transmission.
(A) Stressed mice showed similar AMPAR/NMDAR ratio as non-stressed controls. Representative traces show AMPAR/NMDAR ratio in non-stressed controls (con) and stressed mice (scale bars = 10 pA, 50 ms for ratio). (B) Stressed mice showed similar electrically-evoked NMDAR EPSC peak amplitude as non-stressed controls. Representative traces show EPSCs recorded from non-stressed controls and stressed mice (scale bars = 20 pA, 200 ms). (C) Representative traces show spontaneous EPSCs recorded from non-stressed controls (con) and stressed mice (scale bars = 200 pA, 100 ms). Stressed mice showed normal spontaneous EPSC amplitude (D) but significantly increased spontaneous EPSC frequency (E), as compared to non-stressed controls. Data are means ± SEM. *P < .05 stress versus non-stressed controls. n = 8–9 per group.