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. Author manuscript; available in PMC: 2014 Sep 22.
Published in final edited form as: Alcohol Clin Exp Res. 2009 Jul 1;33(10):1671–1689. doi: 10.1111/j.1530-0277.2009.01004.x

Figure 3.

Figure 3

The relative volume (cc) of the frontal lobe was significantly smaller in the FAS/PFAS group (after exclusion of the two subjects with ACC/HCC) compared to each of the other study groups. The FAS/PFAS group is the only group with the full FAS facial phenotype. Morphogenesis of the middle and upper face is heavily influenced by signals emanating from the forebrain to the frontonasal prominence (Marcucio et al., 2005). The frontonasal prominence is the purple region in the insert depicting a 5-week (left) and 10-week (right) fetus (Moore et al., 1994). C.I.: confidence interval.