Methods	Randomisation: dietitian allocated by opening a sealed envelope containing a card which indicated a diet to be advised (following the taking of a diet history by that dietitian) Allocation concealment: Unclear Participants masked: No Providers masked: No Outcome assessors masked: Yes Summary risk of bias: medium or high
Participants	N: 1015 int., 1018 Control Level of risk for CVD: High (post-MI) Male: 100% Mean age, sd: 56.7 int., 56.4 control Age range: Unclear Smokers: 61.7% int., 62.2% control Hypertension: 22.7% int., 24.6% control Location: UK
Interventions	Type: dietary advice (to eat more oily fish) Intervention: Advised to eat at least 2 weekly portions of 200-400g fatty fish (mackerel, herring, kipper, pilchard, sardine, salmon, trout). If this was not possible, given MaxEPA capsules, 3/d (0.5g EPA/d). 191 of 883 participants were taking MaxEPA at 2 years. Advice was reinforced 3-monthly. Control: No such dietary advice or capsules. Compliance: 7 day weighed food diary of a random sub-sample indicated intake of 2.5g/week EPA int., 0.8g/week EPA control. Length of intervention: 24 mo
Outcomes	Main study outcome: total mortality, reinfarction, CV death Dropouts: none for mortality Available outcomes: total and CV deaths, MI, combined CV events Response to contact: Yes
Notes	Some of each group were also advised on low fat and/or high fibre diets, all participants who smoked were advised to stop and all with a BMI >30 were given weight reduction advice, regardless of randomisation arm
Risk of bias
Item	Authors’ judgement	Description
Allocation concealment?	Unclear	B - Unclear