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. Author manuscript; available in PMC: 2014 Sep 22.
Published in final edited form as: Cochrane Database Syst Rev. 2010 Jun 16;(6):CD001318. doi: 10.1002/14651858.CD001318.pub2
Methods RCT
Participants 55 women with CIN
Interventions Radical diathermy
LLETZ
Outcomes Duration of blood loss
Duration of watery/ blood stained discharge
Duration of yellow discharge
Duration of upper abdominal pain
Duration of lower abdominal pain
Duration of deep pelvic pain
Duration of vaginal pain
Notes
Risk of bias
Item Authors’ judgement Description
Adequate sequence generation? Yes Patients were, “assigned a treatment using … random numbers table”
Allocation concealment? Yes “They were then assigned a treatment using sealed envelopes”
Blinding?
All outcomes
Yes “The treatments were colour coded so the patients and the investigators collecting and analysing the data were blinded to the treatment mode”
Incomplete outcome data addressed?
All outcomes
Yes % of women analysed: 48/55 (87%)
By treatment arm
Radical diathermy: 24/26 (92%)
LLETZ: 24/29 (83%)
Free of selective reporting? Unclear Insufficient information to permit judgement
Free of other bias? Unclear Insufficient information to assess whether an important risk of bias exists