Methods	RCT
Participants	240 women with CIN 1,2,3. All procedures were done as in-patients Mean age in the trial was 32.5 years (SD=8 years). There were 9 (3.75%) women with CIN 1, 71 (30%) with CIN 2, 152 (63%) with CIN 3, 6 (2.5%) women had stage Ia cervical cancer and 2 (0.75%) women had negative histology
Interventions	Knife conisation: wound was sutured with two semicircular sutures (Vicryl, Ethicon, Edinburgh, UK), thus reconstructing the cervix LLETZ: performed using an Elektrotom 400 unit (Brechtold, Tuttlingen, Germany) with loop devices ranging in size from 10 to 20mm. The procedure was performed using a blended current with the cut frequency set at 40 W and the coagulation frequency set between 20 and 40 W
Outcomes	Completeness of excision (endo/ectocervial disease involvement) Adequate colposcopy rates after treatment Primary haemorrhage
Notes	120 randomised to Knife cone 120 randomised to LLETZ
Risk of bias
Item	Authors’ judgement	Description
Adequate sequence generation?	Unclear	Not reported
Allocation concealment?	Unclear	Not reported
Blinding? All outcomes	Unclear	Not reported
Incomplete outcome data addressed? All outcomes	Yes	% of women analysed: 120/120 (100%)
Free of selective reporting?	Unclear	Insufficient information to permit judgement
Free of other bias?	Unclear	Insufficient information to assess whether an important risk of bias exists