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. Author manuscript; available in PMC: 2014 Sep 22.
Published in final edited form as: Cochrane Database Syst Rev. 2010 Jun 16;(6):CD001318. doi: 10.1002/14651858.CD001318.pub2

Comparison 3.

Laser conisation versus knife conisation

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Residual Disease (All Grades of CIN) 2 194 Risk Ratio (IV, Random, 95% CI) 0.64 [0.22, 1.90]
2 Primary Haemorrhage 2 306 Risk Ratio (IV, Random, 95% CI) 0.53 [0.18, 1.54]
3 Secondary Haemorrhage 3 359 Risk Ratio (IV, Random, 95% CI) 0.91 [0.34, 2.40]
4 Inadequate Colposcopy at Follow-up 2 160 Risk Ratio (IV, Random, 95% CI) 0.57 [0.39, 0.81]
5 Cervical Stenosis at Follow-up 4 1007 Risk Ratio (IV, Random, 95% CI) 0.38 [0.19, 0.76]
6 Significant Thermal Artifact Prohibiting Interpretation of Resection Margin 1 Risk Ratio (IV, Random, 95% CI) Subtotals only