Comparison 5.

Laser conisation versus loop excision

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Residual Disease	4	889	Risk Ratio (IV, Random, 95% CI)	1.24 [0.77, 1.99]
2 Duration of Procedure	3	419	Mean Difference (IV, Random, 95% CI)	11.66 [1.37, 21.95]
3 peri-operative severe bleeding	1		Risk Ratio (IV, Random, 95% CI)	Subtotals only
4 Peri-operative Severe Pain	2	594	Risk Ratio (IV, Random, 95% CI)	4.34 [0.25, 75.67]
5 Secondary Haemorrhage	4	889	Risk Ratio (IV, Random, 95% CI)	1.41 [0.72, 2.76]
6 Significant Thermal Artefact on Biopsy	2	373	Risk Ratio (IV, Random, 95% CI)	2.38 [0.61, 9.34]
7 Depth of Thermal Artifact	1		Mean Difference (IV, Random, 95% CI)	Subtotals only
8 Inadequate Colposcopy	2	339	Risk Ratio (IV, Random, 95% CI)	1.38 [0.48, 3.97]
9 Cervical Stenosis	3	560	Risk Ratio (IV, Random, 95% CI)	1.21 [0.57, 2.57]
10 Vaginal discharge	1		Risk Ratio (IV, Random, 95% CI)	Subtotals only