| Methods | RCT | |
| Participants | 289 women with CIN I,II,III | |
| Interventions | Laser ablation LLETZ |
|
| Outcomes | Residual/recurent disease Primary haemorrhage Duration of pregnancy |
|
| Notes | 134 allocated to laser ablation. 120 received allocated treatment 155 allocated to LLETZ 151 received allocated treatment |
|
| Risk of bias | ||
| Item | Authors’ judgement | Description |
| Adequate sequence generation? | Yes | “Consecutively numbered, sealed, opaque envelopes were used to allocate women to treatment with loop diathermy excision of the transformation zone or laser vaporisation according to a computer generated randomisation schedule stratified by centre” |
| Allocation concealment? | Yes | “Consecutively numbered, sealed, opaque envelopes were used” |
| Blinding? All outcomes |
Unclear | Not reported |
| Incomplete outcome data addressed? All outcomes |
Yes | % of women analysed: 285/289 (99%) |
| Free of selective reporting? | Unclear | Insufficient information to permit judgement |
| Free of other bias? | Unclear | Insufficient information to assess whether an important risk of bias exists |