Fig. 3. Ghrelin effects on cAMP levels of C2C12 cells treated with CRF-R1 or CRFR2 selective ligands.
Ucn3, but not stressin or CRF, stimulated cAMP accumulation in C2C12 cells pretreated with ghrelin (A–C). Ucn3, but not CRF, stimulated pERK activation in ghrelin pretreated C2C12 cells (D–E). Each panel shows the data from a representative of at least three experiments. * p<0.05 vs. control.
