Table 1.

Consensus panel recommendations for HER2 scoring in gastric/esophageal cancer.

Score	Specimen	HER2 overexpression assessment
0	No reactivity or membranous reactivity in <10% of cells (resection): in biopsies only one cohesive cluster of >5 cells is required.	Negative
1+	Faint membranous reactivity in >10% of tumor cells (resection): in biopsies only one cohesive cluster of >5 cells is required.	Negative
2+	Weak to moderate incomplete (basolateral) membranous staining in >10% of tumor cells (resection): in biopsies only one cohesive cluster of >5 cells is required.	Equivocal
3+	Moderate to strong incomplete (basolateral) membranous staining in >10% of tumor cells (resection): in biopsies only one cohesive cluster of >5 cells is required.	Positive