Fig. 3.

Acute systemic inflammation decreases proliferation of DCX⁺ cells in the SGZ of WT and p21^-/- mice. A) The confocal image shows that DCX⁺ cells (cytoplasmic, red) are more abundant in the SGZ of p21^-/- hippocampus; B) Number of DCX⁺ cells; C) Number of BrdU⁺ cells; D) Number of DCX⁺ BrdU⁺ cells in WT and p21^-/- SGZ after LPS treatment. For each sample hippocampi from 5 mice/group were analyzed. Data are presented as a mean ± SEM, *, p<0.05; NS, normal saline.