Table 4.
Histopathological and parasitological evaluation of the cervical lymph nodes in cases of canine visceral leishmaniasis. Analyses of presence quantification (P) and grading (G) of tissue abnormalities following the distribution: slight (S), moderate (M) and severe (SV)
| Symptomatic n = 19 | Asymptomatic n = 11 | Control n = 9 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Grading | aP ≤ 0.05 | Grading | aP ≤ 0.05 | Grading | |||||||
| Histopathology | S | M | SV | G/P | S | M | SV | G/P | S | M | SV |
| Inflammation | 7 | 9 | 3 | * **/* ** | 4 | 3 | 0 | */* | 0 | 0 | 0 |
| Macrophages hyperplasic | 2 | 12 | 2 | */* | 2 | 8 | 1 | */* | 0 | 0 | 0 |
| Hypertrophy/hyperplasic of nodules (lymphatic follicles) | 2 | 4 | 4 | */* | 4 | 2 | 2 | */* | 0 | 0 | 0 |
| Hypertrophy/hyperplasia medullar sinus/cords | 3 | 11 | 5 | */* | 3 | 8 | 0 | */* | 0 | 0 | 0 |
| Haemosiderin | 8 | 3 | 4 | *.**/* ** | 1 | 1 | 1 | */* | 0 | 0 | 0 |
| Congestion | 3 | 5 | 2 | */* | 2 | 4 | 2 | */* | 0 | 0 | 0 |
| Fibrosis (μm2)b | 1943 ± 392* | 1596 ± 261 | 1280 ± 3217 | ||||||||
| Parasitological diagnosisb | 28 ± 3** | 6.7 ± 2 | |||||||||
a
Significant differences (P ≤ 0.05) relative to control are represented by * and relative to asymptomatic by**.
b
Values are shown as mean ± standard deviation.