Table 5.
Correlation between presence of histopathology and tissue antioxidant enzyme or iron in canine visceral leishmaniasis
| Liver | Spleen | Lymph node | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Tissue histopathology | CAT | SOD | GSH-Px | Fe | CAT | SOD | GSH-Px | Fe | CAT | Fe |
| Inflammation | −0.735 | −0.768 | −0.781 | 0.659 | −0.723 | −0.584 | −0.787 | 0.780 | −0.729 | − |
| Degeneration | − | − | − | 0.758 | − | − | − | − | − | − |
| Haemosiderin | − | − | − | 0.597 | −0.659 | −0.653 | −0.783 | 0.677 | − | 0.729 |
| Congestion | − | – | − | − | −0.696 | −0.624 | −0.774 | 0.723 | − | − |
| Fibrosis | −0.677 | −0.598 | −0.699 | 0.598 | −0.648 | −0.685 | −0.598 | 0.678 | 0.726 | |
Table represented only Spearman's significant correlation coefficients (P < 0.01). Without significant correlation (−). Antioxidant enzyme: CAT, catalase; SOD, Cu-Zn superoxide dismutase, GSH-Px, glutathione peroxidase; Fe, iron; NO, nitric oxide; LPO, lipid peroxidation.