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. 2014 Sep 22;9(9):e107109. doi: 10.1371/journal.pone.0107109

Figure 5. Comparison of ovarian HGSC and CCC.

Figure 5

Representative hematoxylin and eosin staining of ovarian HGSC and CCC. We hypothesise that these subtypes represents extreme forms of EOC; HGSC generally display positive expression of PGC1α, TFAM and ERα, have a higher Ki-67 index and are more responsive to initial platinum/taxane chemotherapy. By contrast, CCC generally do not express PGC1α, TFAM and ERα, have a lower Ki-67 index and are less responsive to initial platinum/taxane chemotherapy. Magnification 400x, scale bar shows 50 µm.