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. 2014 Sep 22;9(9):e107167. doi: 10.1371/journal.pone.0107167

Figure 4. The relationship of serum IL-6 concentration to T cells and CMV titer (n = 28).

Figure 4

A) Serum IL-6 was negatively associated with absolute counts of CD3+, CD4+, CD8+ lymphocytes and to naïve CD8+ CD45RA+ cells (r≥−0.46, P≤0.01). As IL-6 increased the number of naive CD4+ cells decreased, although not significantly (r = −0.35, P = 0.069). The black line represents the results of linear regression analysis for CD3+, the black dashed line for CD4+, the black dotted line for CD8+, the grey line for CD4+ CD45RA+ and grey dashed line for CD8+ CD45RA+ lymphocyte subtypes. B) Serum IL-6 was positively correlated with CMV titer (r = 0.49, P<0.01). The black line represents the results of linear regression analysis.