Skip to main content
. Author manuscript; available in PMC: 2014 Sep 22.
Published in final edited form as: Cochrane Database Syst Rev. 2010 Apr 14;(4):CD008053. doi: 10.1002/14651858.CD008053.pub2
Methods RCT.
Participants Setting: hospitals in Ontario, Canada.
Inclusion criteria: women with PPROM < 37 weeks, singleton viable pregnancy, cephalic presentation, were admitted and observed for 48-72 hrs. They were included if not in labour, no cervical dilation, no evidence of clinical chorioamnionitis, no evidence of meconium, if less than 34 weeks’ gestation then mother must live within 15 min of emergency care facilities, patient able to self-monitor
(Only 11% of women attending study hospitals with PPROM were eligible for inclusion.)
Interventions 61 women randomised.
Intervention group: discharge home after monitoring period.
Comparison group: inpatient care.
Outcomes Latency period (PPROM to delivery), gestational age at delivery, induction of labour, CS, chorioamnionitis, time in hospital and costs
Notes Study was reported in brief abstracts; there was little information on methods or on management
Risk of bias
Item Authors’ judgement Description
Adequate sequence generation? Unclear Not described.
Allocation concealment? Unclear Not described.
Incomplete outcome data addressed?
All outcomes
Unclear Not described.
Free of selective reporting? Unclear Study reported in a series of brief abstracts.

CS: caesarean section

hrs: hours

min: minutes

NICU: neonatal intensive care unit

NST: non-stress test

PPROM: preterm prelabour rupture of membranes

RCT: randomised controlled trial