Comparison 1.
Topical imiquimod versus placebo
| Outcome or subgroup title | No. of studies | No. of participants | Statistical method | Effect size |
|---|---|---|---|---|
| 1 Response to treatment at 5-6 months | 3 | 104 | Risk Ratio (IV, Random, 95% CI) | 11.95 [3.21, 44.51] |
| 2 Response to treatment at 12 months | 1 | Risk Ratio (IV, Random, 95% CI) | Subtotals only | |
| 3 Progression to vulvar cancer at 12 months | 1 | Risk Ratio (IV, Random, 95% CI) | Subtotals only | |
| 4 Pain due to disease | 1 | Risk Ratio (IV, Random, 95% CI) | Subtotals only | |
| 5 Pruritis due to disease | 1 | Risk Ratio (IV, Random, 95% CI) | Subtotals only | |
| 6 Mild to moderate Erythema | 1 | Risk Ratio (IV, Random, 95% CI) | Subtotals only | |
| 7 Erosion | 1 | Risk Ratio (IV, Random, 95% CI) | Subtotals only | |
| 8 Pain or pruritus | 1 | Risk Ratio (IV, Random, 95% CI) | Subtotals only | |
| 9 Local side effects | 1 | Risk Ratio (IV, Random, 95% CI) | Subtotals only |