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. 2014 Apr 23;6(4):991–999. doi: 10.4161/mabs.28841

graphic file with name mabs-6-991-g2.jpg

Figure 2. XmAb5871 inhibits while XENP6187 enhances calcium mobilization when CD19 is coligated with BCR. Fluo-4 loaded B cells were treated with either XmAb5871 or the Fc-KO XENP6187 antibodies and then stimulated with 10 μg/ml anti-Ig. Calcium flux kinetics was recorded using FACSCalibur flow cytometer and data were analyzed by FlowJo software. Data represent the average of two independent experiments.