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. 2014 Sep 22;9(9):e107193. doi: 10.1371/journal.pone.0107193

Table 1. Clinical differences between discovery and validation studies.

Studies
Discovery Validation
TCGA Tothill Yoshihara
N 503 240 260
Age Mean 59.8 60.2 NA Inline graphic
Stage I, II 24 9 0
III, IV 463 215 260 Inline graphic *
Grade 1 4 5 0
2,3 473 218 260 Inline graphic**
Cytoreduction Optimal 102 53 103
Suboptimal 348 140 157 Inline graphic +
Follow Up
OS Median 30 28 41.5
PFS Median 13.2 14 19

*excludes Yoshihara data, p-value  = .001597 when including Yoshihara data.

+

definition of optimal/suboptimal not clearly defined in Yoshihara data.