Methods	R, DB, double dummy, single oral dose, five parallel groups. Medication administered when baseline pain was of moderate to severe intensity Pain assessed at 0, 15, 30, 45, 60, 90 min, 2, 3, 4, 5, 6 h.
Participants	Surgical removal of impacted third molars N = 206 M = 66, F = 140 Mean age = 25 years
Interventions	Ketoprofen 12.5 mg, n = 42 Ketoprofen 25 mg, n = 41 Paracetamol 500 mg, n = 41 Paracetamol 1000 mg, n = 41 Placebo, n = 41
Outcomes	PGE: non std 4 point scale Time to use of rescue medication Number using rescue medication Adverse events: any, serious Withdrawals
Notes	Oxford Quality Score: R1, DB2, W1 12 h analgesic washout before surgery