1.7. Analysis.
Comparison 1 Fluvoxamine versus TCAs, Outcome 7 Depression scale ‐ Endpoint score: low=good (acute phase) ‐ missing SDs or skewed data.
| Depression scale ‐ Endpoint score: low=good (acute phase) ‐ missing SDs or skewed data | ||||||||
|---|---|---|---|---|---|---|---|---|
| Study | Depression scale | Fluvoxamine; mean | SD | n | comparator; mean | SD | n | Note |
| vs Imipramine | ||||||||
| Claghorn 1996 | HRSD‐21 | 16 | missing | 44 | 15.5 | missing | 44 | |
| Fabre 1996 | HRSD‐21 | 14.2 | missing | 46 | 14.3 | missing | 48 | |
| Feighner 1989 | HRSD‐17 | 10.5 | missing | 21 | 16.4 | missing | 27 | |
| Guy 1984 | HRSD‐17 | 13.0 | missing | 16 | 12.1 | missing | 16 | |
| Lydiard 1989 | HRSD‐17 | 12.8 | missing | 17 | 9.0 | missing | 18 | |
| March 1990 | HRSD‐17 | 12.5 | missing | 13 | 13.8 | missing | 15 | |
| vs Clomipramine | ||||||||
| de Wilde 1983 | HRSD‐17 | 6.4 | missing | 21 | 5.1 | missing | 21 | |
| Zohar 2003 | HRSD‐17 | 13.4 | missing | 42 | 12.3 | missing | 42 | |
| vs Amitriptyline | ||||||||
| Barge‐Schaapveld 1995 | HRSD‐17 | 10.0 | 5.2 | 11 | 8.6 | 8.0 | 10 | skewed. |
| Harris 1991a | HRSD‐17 | 10.4 | missing | 6.6 | missing | 26 | ||
| Kostiukova 2003 | HRSD‐17 | 7.4 | missing | 30 | 6.7 | missing | 30 | |
| Remick 1994 | HRSD‐17 | 8.7 | 7.2 | 13 | 10.3 | 6.0 | 10 | skewed. |
| vs Nortriptyline | ||||||||
| Otsubo 2005 | HRSD‐17 | 11.9 | 8.9 | 36 | 12.1 | 5.9 | 38 | skewed. |
| vs Dothiepin | ||||||||
| Mullin 1988 | HRSD‐17 | 8.3 | missing | 26 | 8.5 | missing | 24 | |
| Rahman 1991 | MADRS | 13.5 | missing | 19 | 14.4 | missing | 21 | |
| vs Desipramine | ||||||||
| Tourigny‐Rivard 1996 | HRSD‐17 | 4.9 | missing | 22 | 10.8 | missing | 25 | |