Table 2.
Diagnostic performance of EUS, cytology, CEA and CA 19-9 fluid levels in identifying premalignant of malignant cystic lesions mean 95% CI (%)
| EUS alone | Cytology | CEA > 3.1 ng/mL1 | CA 19-9 > 37 U/mL1 | |
| Sensitivity | 50 (16-84) | 71 (49-92) | 70 (42-98) | 75 (33-75) |
| Specificity | 56 (30-80) | 96 (87-99) | 85 (65-99) | 90 (71-99) |
| Negative predictive value | 69 (39-91) | 82 (62-94) | 79 (57-99) | 75 (43-95) |
| Positive predictive value | 36 (11-69) | 92 (64-99.8) | 78 (51-99) | 90 (56-99.8) |
| Accuracy | 54 (34-74) | 85 (74-96) | 78 (61-95) | 82 (66-98) |
| Area under curve | 0.53 (0.32-0.74) | 0.83 (0.68-0.93) | 0.78 (0.54-0.93) | 0.8 (0.57-0.94) |
1
Optimal cut-offs for CEA and CA 19-9 as determined by receiver-operator characteristic (ROC) curve analysis.